Disorders of fatty acid oxidation include;
A. Carnitine deficiency
B. Carnitine deficiency
C. Ketoacidosis
D. All of the above
Answer: D
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Thiolytic cleavage of β-ketoderivative by an incoming CoA to yield acetyl CoA is catalyzed by;
A. Thiolase
B. β-hydroxyacyl CoA dehydrogenase
C. Enoyl CoA hydratase
D. Acyl CoA dehydrogenase
Answer: A
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The process of β-oxidation of fatty acids includes all but one of the process
A. Oxidation of fatty acyl CoA
B. Hydration of the unsaturated fatty acyl CoA
C. Oxidation of the β-hydroxy derivative
D. None of the above
Answer: D
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All but one is true about the carnitine fatty acyl carrier system
A. Carnitine acyl transferase 1 facilitates synthesis of Acyl carnitine
B. Carninitine acyl translocase transports acyl carnitine across the inner mitochondrial membrane into the matrix
C. Mitochondrial Carnitine acyl transferase II re-synthesizes fatty acyl CoA
D. Free carnitine remains in the mitochondrial matrix
Answer: D
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Oxidative phosphorylation of fatty acids in the TCA cycle requires which of the following;
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Which is not true about cellular fatty acid metabolism?
A. Free fatty acids travels through the blood stream bound to serum albumin
B. Fatty acid activation occurs in the cytosol as fatty acyl CoAs
C. Fatty acid oxidation occurs in the mitochondrial matrix
D. None of the above
Answer: D
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Mobilization of free fatty acids from fat stores is herald by all these mechanisms but
A. Activation of intracellular second messenger cascade
B. Phosphorylation of hormone sensitive lipase
C. Lipolysis of triglycerides into glycerol and free fatty acids
D. None of the above
Answer: D
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Fatty Acid Activation is triggered by all these hormones except
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During prolonged fasting, the body source its major metabolic fuel through which of the following metabolic events;
A. Hepatic conversion of acetyl coA from FA oxidation
B. Amino acid breakdown to ketone bodies
C. Hepatic and skeletal muscle glycogenesis
D. Hepatic gluconeogenesis
Answer: C
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Utilization of fatty acids for energy production is absent in which of these tissues
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